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  giant cell tumor-like lesion of the urinary bladder: a report of two cases and literature review; giant cell tumor or undifferentiated carcinoma? order cheap generic viagra Giant cell tumor, excluding its prototype in bone, is usually a benign but local aggressive neoplasm originating from tendon sheath or soft tissue. viagra online australian pharmacy Malignant behavior is uncommon. Visceral organ involvement including urinary bladder is rare. Giant cell tumors in visceral organs usually accompany epithelial tumors and the clinical behavior of giant cell tumor in urinary bladder is similar to its bone counterpart. Here, we report two cases of giant cell tumor located in urinary bladder in comparison with nine reported cases in the english literature. Concurrent noninvasive urothelial carcinoma was also described in all these previous reports and only one patient with follow-up died of disease. viagra glaxosmithkline bayer One of the two cases we present had no concurrent urothelial tumor at the time of diagnosis but had a history of a low grade noninvasive urothelial carcinoma with three recurrences. The histology of these two cases was similarto the giant cell tumor of bone and composed of oval to spindle mononuclear cells with evenly spaced osteoclast-like giant cells. Immunohistochemically, the giant cells showed staining with osteoclastic markers including cd68, trap, and lca. viagra delivered overnight Immunohistochemical expression of vimentin, cd68, lca, and smooth muscle actin in mononuclear cells supported a mesenchymal origin with histiocytic lineage. viagra online australian pharmacy The histologic and immunohistochemical properties in our cases as well as their clinical courses were consistent with a giant cell tumor. Consequently, tumors in urinary bladder showing features of giant cell tumor of bone may also be considered and termed "giant cell tumor". Author: kemal behzatogluhaydar duraksule canberkovgu aydingulben erdem huqmeltem oznurgul ozyalvaclipelin yildizcredits/source: diagnostic pathology 2009, 4:48 published on: 2009-12-31 tweet copyright by the authors listed above - made available via biomedcentral (open access). Please make sure to read our disclaimer prior to contacting 7thspace interactive. free viagra trial sample To contact our editors, visit our online helpdesk. does health insurance pay for viagra If you wish submit your own press release, click here. Social bookmarking retweet this! buying viagra online | digg this! | post to del. Icio. Us | post to furl | add to netscape | add to yahoo! | rojo comments there are no comments available. Be the first to write a comment. cheap viagra online You need to enable javascript to post a comment. Your name your email address your comment (500 characters left) reload image type. order viagra .